FANDOM


Irc 370468 1487959756 S1 tokens 11716

tokens' monocyte protein from Puzzle 1343.

Monocyte is a Foldit revisiting puzzle, originally presented as Puzzle 88: Monocyte in 2008.

The protein in this puzzle is from a human monocyte, a type of white blood cell.

The puzzle protein has 71 segments with the sequence:

mqpdainapvtccynftnrkisvqrlasyrritsskcpkeavifktivakeicadpkqkwvqdsmdhldkq

The sequence is found in these Protein Data Bank entries:

  • 4R8I (chain A, offset 0)
  • 1DOL (chain A, offset 0)
  • 1DOK (chains A, B; offset 0)

The puzzle protein can have two disulfide bridges, identified in 4R8I as 11-36, and 12-52. The model in 4R8I omits the methionine which appears at segment 1 in the puzzle, so you must add one to the residue numbers in the PDB. Similarly, the model for 1DOL has the methionine as residue 0, so once again you must add one to get the Foldit segment number.

In recent visits to this puzzle, each bridge is awarded a bonus of 250 points.

The recipe Bridge Wiggle v 1.2.1 - Brow42 accepts the (corrected) bridges in this format:

13,53 12,37

This puzzle does not have any ligands.

This puzzle has a single chain.

See players' solutions from previous visits this puzzle: