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[[File:Irc 476462 1431731023 G1 Beta Folders E1 LociOiling.png|thumb|400px|LociOiling's dihydrolipoamide succinyltransferase core from [[Puzzle 1086|puzzle 1086]].]] |
[[File:Irc 476462 1431731023 G1 Beta Folders E1 LociOiling.png|thumb|400px|LociOiling's dihydrolipoamide succinyltransferase core from [[Puzzle 1086|puzzle 1086]].]] |
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− | [[Revisiting_puzzle/Glycolysis|Glycolysis]] is a [[Revisiting puzzle|revisiting puzzle]], originally presented in 2008 as [https://fold.it/portal/node/375147 Puzzle 72: Glycolysis]. |
+ | [[Revisiting_puzzle/72: Glycolysis|72: Glycolysis]] is a [[Revisiting puzzle|revisiting puzzle]], originally presented in 2008 as [https://fold.it/portal/node/375147 Puzzle 72: Glycolysis]. |
+ | |||
+ | The recent versions of this puzzle use "citric acid cycle" in the title in place of "glycolysis". |
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[[wikipedia:Glycolysis|Glycolysis]] refers to the process of metabolizing glucose. This small protein is referred to as the "E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of ''Escherichia coli''". |
[[wikipedia:Glycolysis|Glycolysis]] refers to the process of metabolizing glucose. This small protein is referred to as the "E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of ''Escherichia coli''". |
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</pre> |
</pre> |
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− | This sequence is found in the following [[PDB|Protein Data Bank]] |
+ | This sequence is found in the following [[PDB|Protein Data Bank]] entries: |
*[https://www.rcsb.org/structure/1bal 1BAL] (chain A, offset 11) |
*[https://www.rcsb.org/structure/1bal 1BAL] (chain A, offset 11) |
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*[https://www.rcsb.org/structure/1bbl 1BBL] (chain A, offset 11) |
*[https://www.rcsb.org/structure/1bbl 1BBL] (chain A, offset 11) |
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− | *[https://www.rcsb.org/structure/1w4h |
+ | *[https://www.rcsb.org/structure/1w4h 1W4H] (chain A, offset 7) |
*[https://www.rcsb.org/structure/2cyu 2CYU] (chain A, offset 1) |
*[https://www.rcsb.org/structure/2cyu 2CYU] (chain A, offset 1) |
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*[[Puzzle 768]] |
*[[Puzzle 768]] |
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*[[Puzzle 1086]] |
*[[Puzzle 1086]] |
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− | *[[Puzzle |
+ | *[[Puzzle 1541]] |
+ | *[[Puzzle 1740]] |
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+ | Complete series of revisits with top scores: |
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+ | {| class="wikitable" |
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+ | |- |
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+ | !puzzle |
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+ | !closed |
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+ | !top solo score |
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+ | !top solo |
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+ | !top evo score |
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+ | !top evo |
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+ | !top group score |
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+ | !top group |
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+ | !comments |
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+ | |- |
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+ | |[https://fold.it/portal/node/375147 72: Glycolysis] |
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+ | |08/18/08 |
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+ | |8,862 |
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+ | |Steven Pletsch |
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+ | |8,889 |
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+ | |MattSaffell |
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+ | |8,889 |
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+ | |Another Hour Another Point |
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+ | | |
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+ | |- |
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+ | |[https://fold.it/portal/node/995825 768: Revisiting Puzzle 72: Glycolysis] |
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+ | |09/03/13 |
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+ | |8,957 |
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+ | |martinzblavy |
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+ | |8,961 |
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+ | |gitwut |
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+ | |8,961 |
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+ | |Contenders |
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+ | | |
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+ | |- |
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+ | |[https://fold.it/portal/node/2000696/ 1086: Revisiting Puzzle 72: Citric Acid Cycle] |
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+ | |05/15/15 |
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+ | |8,473 |
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+ | |reefyrob |
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+ | |8,473 |
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+ | |LociOiling |
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+ | |8,473 |
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+ | |Beta Folders |
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+ | | |
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+ | |- |
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+ | |[https://fold.it/portal/node/2002872 1289: Revisiting Puzzle 72: Citric Acid Cycle] |
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+ | |10/05/16 |
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+ | |8,641 |
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+ | |LociOiling |
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+ | |8,645 |
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+ | |bertro |
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+ | |8,646 |
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+ | |Beta Folders |
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+ | | |
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+ | |- |
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+ | |[https://fold.it/portal/node/2005456 1541: Revisiting Puzzle 72: Citric Acid Cycle] |
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+ | |07/09/18 |
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+ | |9,213 |
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+ | |retiredmichael |
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+ | |9,217 |
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+ | |LociOiling |
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+ | |9,217 |
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+ | |Beta Folders |
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+ | | |
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+ | |- |
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+ | |[https://fold.it/portal/node/2008187 1740: Revisiting Puzzle 72: Citric Acid Cycle] |
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+ | |10/09/19 |
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+ | |9,213 |
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+ | |Phyx |
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+ | |9,197 |
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+ | |NinjaGreg |
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+ | |9,213 |
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+ | |Go Science |
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+ | | |
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+ | |} |
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[[Category:Revisiting Puzzle]] |
[[Category:Revisiting Puzzle]] |
Revision as of 16:51, 19 March 2020
72: Glycolysis is a revisiting puzzle, originally presented in 2008 as Puzzle 72: Glycolysis.
The recent versions of this puzzle use "citric acid cycle" in the title in place of "glycolysis".
Glycolysis refers to the process of metabolizing glucose. This small protein is referred to as the "E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli".
The puzzle has 37 segments with the sequence:
lspairrllaehnldasaikgtgvggrltredvekhl
This sequence is found in the following Protein Data Bank entries:
- 1BAL (chain A, offset 11)
- 1BBL (chain A, offset 11)
- 1W4H (chain A, offset 7)
- 2CYU (chain A, offset 1)
This puzzle does not have any disulfide bridges.
This puzzle does not have any ligands.
This puzzle has a single chain.
See players' solutions from previous visits to this puzzle:
Complete series of revisits with top scores:
puzzle | closed | top solo score | top solo | top evo score | top evo | top group score | top group | comments |
---|---|---|---|---|---|---|---|---|
72: Glycolysis | 08/18/08 | 8,862 | Steven Pletsch | 8,889 | MattSaffell | 8,889 | Another Hour Another Point | |
768: Revisiting Puzzle 72: Glycolysis | 09/03/13 | 8,957 | martinzblavy | 8,961 | gitwut | 8,961 | Contenders | |
1086: Revisiting Puzzle 72: Citric Acid Cycle | 05/15/15 | 8,473 | reefyrob | 8,473 | LociOiling | 8,473 | Beta Folders | |
1289: Revisiting Puzzle 72: Citric Acid Cycle | 10/05/16 | 8,641 | LociOiling | 8,645 | bertro | 8,646 | Beta Folders | |
1541: Revisiting Puzzle 72: Citric Acid Cycle | 07/09/18 | 9,213 | retiredmichael | 9,217 | LociOiling | 9,217 | Beta Folders | |
1740: Revisiting Puzzle 72: Citric Acid Cycle | 10/09/19 | 9,213 | Phyx | 9,197 | NinjaGreg | 9,213 | Go Science |