Top7 is a protein designed by scientists at the Baker Lab at the University of Washington, and published in 2003. It has a "novel fold", meaning that no natural proteins are folded in a similar pattern.
This protein was the PDB's Molecule of the Month for October 2005
The puzzle has 92 segments with the sequence:
The sequence is at offset 2 of chain A in 1QYS, meaning segment 1 of the protein in Foldit is residue 3 of 1QYS. The model for 1QYS actually starts with residue 3 and runs to residue 94. The sequence for 1QYS shows 106 residues, but only residues 3 to 94 are present in the model.
This puzzle does not have any disulfide bridges.
This puzzle does not have any ligands.
This puzzle is a single chain.
See players' solutions from previous visits to this puzzle:
Complete series of revisits with top scores:
|puzzle||closed||top solo score||top solo||top evo score||top evo||top group score||top group||comments|
|61: Designer Protein Top7||06/12/08||10,572||sirenbrian||10,572||Another Hour Another Point|
|710: 5-year-anniversary puzzle: 2008||05/14/13||10,982||wisky||10,982||Hanto_FZ140E_4G||10,982||Clear The Way||start year 2003?!?|
|1056: Revisiting Puzzle 61: Designer Protein Top7||02/26/15||9,840||LociOiling||9,845||retiredmichael||9,845||Beta Folders|
|1259: Revisiting Puzzle 61: Designer Protein Top7||07/20/16||10,064||LociOiling||10,066||Bletchley Park||10,066||Contenders|
|1512: Revisiting Puzzle 61: Designer Protein Top7||04/30/18||11,691||ZeroLeak7||11,700||Galaxie||11,700||Anthropic Dreams|
|1545: Sketchbook Puzzle - Revisiting Puzzle 61: Designer Protein Top7||07/09/18||11,651||Timo van der Laan||11,659||LociOiling||11,659||Beta Folders|
|1702: Revisiting Puzzle 61: Designer Protein Top7||07/29/19||11,733||johnmitch||11,749||ManVsYard||11,749||Gargleblasters|