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(Original puzzle number now part of the name.)
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[[File:Pdb_1b7k.png|thumb|400px|The eelpout AFP [https://www.rcsb.org/structure/1b7k 1B7K], as seen in JMol.]]
 
[[File:Pdb_1b7k.png|thumb|400px|The eelpout AFP [https://www.rcsb.org/structure/1b7k 1B7K], as seen in JMol.]]
[[Revisiting_puzzle/Ice Binding|Ice Binding]] is a [[Revisiting puzzle|revisiting puzzle]], originally presented in 2009 as [https://fold.it/portal/node/960281 Puzzle 125: Ice Binding].
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[[Revisiting_puzzle/125: Ice Binding|125: Ice Binding]] is a [[Revisiting puzzle|revisiting puzzle]], originally presented in 2009 as [https://fold.it/portal/node/960281 Puzzle 125: Ice Binding].
   
 
The puzzle involves an antifreeze protein (AFP) from the fish ''Zoarces americanus'', the largest member of the [[wikipedia:Eelpout|eelpout]] family. The protein binds to ice to help protect the fish from freezing.
 
The puzzle involves an antifreeze protein (AFP) from the fish ''Zoarces americanus'', the largest member of the [[wikipedia:Eelpout|eelpout]] family. The protein binds to ice to help protect the fish from freezing.
   
The same protein also appears in the [[Revisiting_puzzle/Antifreeze_Protein|Antifreeze Protein]] puzzle.
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The same protein also appears in the [[Revisiting_puzzle/75: Antifreeze_Protein|75: Antifreeze Protein]] puzzle.
   
 
The puzzle has 66 segments with the sequence:
 
The puzzle has 66 segments with the sequence:

Revision as of 03:39, July 3, 2019

Pdb 1b7k

The eelpout AFP 1B7K, as seen in JMol.

125: Ice Binding is a revisiting puzzle, originally presented in 2009 as Puzzle 125: Ice Binding.

The puzzle involves an antifreeze protein (AFP) from the fish Zoarces americanus, the largest member of the eelpout family. The protein binds to ice to help protect the fish from freezing.

The same protein also appears in the 75: Antifreeze Protein puzzle.

The puzzle has 66 segments with the sequence:

anqasvvanqlipintaltlvmmrsevvtpvgipaediprlvsmqvnhavplgttlmpdmvkgyaa

This sequence is found in this Protein Data Bank entry:

  • 1B7K. (chain A, offset 0)

This puzzle does not have any disulfide bridges.

This puzzle does not have any ligands.

This puzzle has a single chain.

Unfortunately, no one has posted images of this protein from previous revisits! An image of PDB entry 1B7K as seen in the protein viewer Jmol was used for this page. See Antifreeze Protein for more images.

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