Foldit Wiki
No edit summary
Tag: rte-source
(Add new Loci video.)
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
[[File:Level_8-4_DNA_and_Protein.png|thumb|400px|Level 8-4 DNA and protein. ]]
 
[[File:Level_8-4_DNA_and_Protein.png|thumb|400px|Level 8-4 DNA and protein. ]]
 
DNA can form [[Hydrogen bond|hydrogen bonds]] to protein.
 
DNA can form [[Hydrogen bond|hydrogen bonds]] to protein.
  +
 
'''[http://www.youtube.com/watch?v=3dK2u6iPnhA Madde's "DNA and Protein" video]'''
  +
  +
'''[https://www.youtube.com/watch?v=NqElKNcgBD4 Loci's "DNA and Protein" video]'''
   
 
In this puzzle, there's a section of DNA on the left and a small protein on the right. Two segments of the protein are shown in yellow, and can be mutated in design mode.
 
In this puzzle, there's a section of DNA on the left and a small protein on the right. Two segments of the protein are shown in yellow, and can be mutated in design mode.
Line 6: Line 10:
 
Select Design Mode from the Modes menu. Then click on one of the yellow segments and select a new amino acid. Use the inner blue ring of the mutate wheel to select a [[Hydrophilic|hydrophilic]].
 
Select Design Mode from the Modes menu. Then click on one of the yellow segments and select a new amino acid. Use the inner blue ring of the mutate wheel to select a [[Hydrophilic|hydrophilic]].
   
The help popups suggest a long hydrophilic for one segment, and a shorter, forked hydrophilic for other. [[Lysine]] is a long hydrophilic, and [[Asparagine|asparagine]] is a forked hydrophilic that's shorter than lysine. Check out the [[Amino Acid Gallery (EnzDes coloring)|Amino Acid Gallery]] for all the options.
+
The help popups suggest a long hydrophilic for one segment, and a shorter, forked hydrophilic for other. [[Lysine]] is a long hydrophilic, and [[Asparagine|asparagine]] is a forked hydrophilic that's shorter than lysine. Check out the [[Amino Acid Gallery|amino acid gallery]] for all the options.
   
 
If you pick the correct amino acids, the puzzle is solved. The [[Shake Sidechains|shake]] tool is available, but shouldn't be needed.
 
If you pick the correct amino acids, the puzzle is solved. The [[Shake Sidechains|shake]] tool is available, but shouldn't be needed.
 
[http://www.youtube.com/watch?v=3dK2u6iPnhA Madde's "DNA and Protein" video]
 
 
<br clear="all"/>
 
<br clear="all"/>
 
 
<div align="center">
 
<div align="center">
 
<gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
 
<gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
Level 8-3.png|'''Previous:''' Level 8-3: DNA Pairing|link=Intro_Puzzles/DNA_Pairing
+
DNA_Pairing.png|'''Previous:''' DNA Pairing|link=Intro_Puzzles/DNA_Pairing
 
Intro Success.png|'''Next:''' You're done!|link=Intro_Puzzles
 
Intro Success.png|'''Next:''' You're done!|link=Intro_Puzzles
 
</gallery>
 
</gallery>
Line 22: Line 23:
 
[[Category:Help foldit]]
 
[[Category:Help foldit]]
 
[[Category:Puzzle Types]]
 
[[Category:Puzzle Types]]
  +
[[Category:Intro Puzzle]]

Revision as of 08:07, 9 June 2018

Level 8-4 DNA and Protein

Level 8-4 DNA and protein.

DNA can form hydrogen bonds to protein.

Madde's "DNA and Protein" video

Loci's "DNA and Protein" video

In this puzzle, there's a section of DNA on the left and a small protein on the right. Two segments of the protein are shown in yellow, and can be mutated in design mode.

Select Design Mode from the Modes menu. Then click on one of the yellow segments and select a new amino acid. Use the inner blue ring of the mutate wheel to select a hydrophilic.

The help popups suggest a long hydrophilic for one segment, and a shorter, forked hydrophilic for other. Lysine is a long hydrophilic, and asparagine is a forked hydrophilic that's shorter than lysine. Check out the amino acid gallery for all the options.

If you pick the correct amino acids, the puzzle is solved. The shake tool is available, but shouldn't be needed.