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De_novo puzzles are puzzle where only the primary sequence is known.
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De_novo puzzles are puzzles where only the primary sequence is known. The peptide (chain) is provided as a straight string which players need to analyse and fold. The goal is to get close to a native low energy folded protein.
   
A prediction of the secondary structure is often given in comment with probability that each amino acid is a part of a sheet, an helix or a loop.
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A prediction of the secondary structure is often given in the comments with a probability for each amino acid being a part of a sheet, an helix or a loop.
   
Many strategies are given by players to begin with this type of puzzles in strategies pages and videos.
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Many strategies are given by players to start this type of puzzles in strategies pages and videos.
   
[[Hand folding de novo S pletsch]]
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*[[Hand folding de novo S pletsch]]
   
<p style="color:rgb(51,51,51);font-family:helvetica,sans-serif;line-height:normal;">[http://fold.it/portal/node/996246 Session 7 - Black Belt Folding Postscript]</p>
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<li style="color:rgb(51,51,51);font-family:helvetica,sans-serif;line-height:normal;">[http://fold.it/portal/node/996246 Session 7 - Black Belt Folding Postscript]</li>
   
[http://fold.it/portal/node/996236 Black Belt Folding LIVE from the Pacific Science Center]
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*[http://fold.it/portal/node/996236 Black Belt Folding LIVE from the Pacific Science Center]
   
[[Marie-s strategy for hand folding]]
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*[[Marie-s strategy for hand folding]]
   
[[How to start folding a DeNovo (freestyle) puzzle?]]
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*[[How to start folding a DeNovo (freestyle) puzzle?]]
   
 
[[File:Foldit time-lapse First hour of hand-folding de-novo puzzle 693|thumb|left|335px|Madde hand folding de-novo]]
 
[[File:Foldit time-lapse First hour of hand-folding de-novo puzzle 693|thumb|left|335px|Madde hand folding de-novo]]

Revision as of 08:37, 23 December 2014

De_novo puzzles are puzzles where only the primary sequence is known. The peptide (chain) is provided as a straight string which players need to analyse and fold. The goal is to get close to a native low energy folded protein.

A prediction of the secondary structure is often given in the comments with a probability for each amino acid being a part of a sheet, an helix or a loop.

Many strategies are given by players to start this type of puzzles in strategies pages and videos.

  • Session 7 - Black Belt Folding Postscript
  • Foldit_time-lapse_First_hour_of_hand-folding_de-novo_puzzle_693

    Foldit time-lapse First hour of hand-folding de-novo puzzle 693

    Madde hand folding de-novo








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