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− | De_novo puzzles are |
+ | De_novo puzzles are puzzles where only the primary sequence is known. The peptide (chain) is provided as a straight string which players need to analyse and fold. The goal is to get close to a native low energy folded protein. |
− | A prediction of the secondary structure is often given in |
+ | A prediction of the secondary structure is often given in the comments with a probability for each amino acid being a part of a sheet, an helix or a loop. |
− | Many strategies are given by players to |
+ | Many strategies are given by players to start this type of puzzles in strategies pages and videos. |
− | [[Hand folding de novo S pletsch]] |
+ | *[[Hand folding de novo S pletsch]] |
− | < |
+ | <li style="color:rgb(51,51,51);font-family:helvetica,sans-serif;line-height:normal;">[http://fold.it/portal/node/996246 Session 7 - Black Belt Folding Postscript]</li> |
− | [http://fold.it/portal/node/996236 Black Belt Folding LIVE from the Pacific Science Center] |
+ | *[http://fold.it/portal/node/996236 Black Belt Folding LIVE from the Pacific Science Center] |
− | [[Marie-s strategy for hand folding]] |
+ | *[[Marie-s strategy for hand folding]] |
− | [[How to start folding a DeNovo (freestyle) puzzle?]] |
+ | *[[How to start folding a DeNovo (freestyle) puzzle?]] |
[[File:Foldit time-lapse First hour of hand-folding de-novo puzzle 693|thumb|left|335px|Madde hand folding de-novo]] |
[[File:Foldit time-lapse First hour of hand-folding de-novo puzzle 693|thumb|left|335px|Madde hand folding de-novo]] |
Revision as of 08:37, 23 December 2014
De_novo puzzles are puzzles where only the primary sequence is known. The peptide (chain) is provided as a straight string which players need to analyse and fold. The goal is to get close to a native low energy folded protein.
A prediction of the secondary structure is often given in the comments with a probability for each amino acid being a part of a sheet, an helix or a loop.
Many strategies are given by players to start this type of puzzles in strategies pages and videos.
see others here Gameplay-Videos