Changes: Campaign

Revision as of 21:18, 5 November 2020

Intro Puzzles show you how to play Foldit. This special campaign level shows you how to use many of the tools, and explains some of the key ideas, like Clashes, Voids, and Exposeds.

Try to complete each puzzle without help first. Most of the puzzles should take only a couple of minutes. If you get stuck, use "Reset Puzzle" from the Actions menu in the lower left and try again.

Note: the video QUICK Foldit Tutorial Walkthrough from S0ckrates shows you how to be the boss of the intro puzzles.

Intro Puzzle Tips covers some common questions like how to band and freeze. It also gives some keyboard shortcuts for view options that may help you see what's going on.

If you're having problems, you'll find tips below. Just click on the icon for the puzzle you're stuck on. There are tips and techniques for each puzzle. Each puzzle also YouTube videos provided by Foldit players Madde and Loci.

A few puzzles, such as Remix, Electron Density, and Hydrophobic Disaster, may require more time. These intro puzzles are closer to real Foldit puzzles.

If you have additional questions, ask online in the Foldit client using "Chat - Global", or "Chat - Group". See Foldit chat for more on Foldit chat. The following translations of this page are available: Deutsch | Svenska | Español | German | Russian | Japanese.

The campaign puzzles are arranged in levels. Each level covers a different part of Foldit. You earn a Foldit achievement when you complete a level.

There are different paths through the levels. The paths may allow you to move on to a new level if you get stuck on a particular puzzle. You can always come back later to finish a problem puzzle.

Click on the icons below for more information about each intro puzzle. The Intro Puzzle Master List has the same information in a simplified format.

Sidechains

The puzzles in the Sidechains level introduce sidechains and demonstrate ways to fix clashes. The shake tool makes its debut.

Backbone Packing

The Backbone Packing level introduces the backbone, the part which holds the protein together. The sidechains are attached to the backbone.

This level demonstrates how to fix voids. The wiggle tool is added to the mix. Wiggle and shake are the most important tools in Foldit.

Hydrogen Bonding

The Hydrogen Bonding level introduces hydrogen bonds, which help hold proteins together. Hydrogen bonds show as blue-and-white "candy canes" in Foldit.

This level includes techniques for lining up sheets that are used all the time by Foldit players. It adds bands, which are important for moving sheets and other parts of the protein.

Hydrophobics and Hydrophilics

This level digs itno hydrophobics and hydrophilics in more detail. Orange sidechains are hydrophobic, and should be hidden on the inside of the protein. Blue sidechains are hydrophilic, and are OK on the outside of the protein.

Protein Design

This level introduces Foldit design puzzles, which give players the chance to design new proteins. Some of these designs actually get turned into real proteins in the Foldit lab, see design puzzle results for more.

Conditional Quests

This level covers conditions, which enforce special rules on some puzzles. Conditions may change your score, adding or subtracting points. Conditions were previously called "filters".

Blueprints

This level introduces the blueprint tool, which is used in design puzzles to insert shapes found in natural proteins. The blueprint tool may help players create proteins which fold up on their own like natural ones. Design puzzles are covered in more detail in the next section.

Tools and Types

The Tools and Types level introduces some of the different puzzle types found in Foldit. The move tool is added.

This level also introduces the remix tool, which searches for new shapes for your protein.

Sequences

Sequences introduces the alignment tool. The alignment tool lets you apply the shapes of other proteins to the protein you're working on.

You'll also get to use cuts, which chop a protein into pieces. Cuts are used in all kinds of ways in Foldit.

More Molecules

The More Molecules level introduces ligands. A ligand is a non-protein atom or molecule. A ligand can be as small as copper or calcium atom, or as large as a strand of DNA.

These puzzles work with fixed ligands that can't be changed. A new small molecule design feature is in development for Foldit. This will allow the ligand to be designed, much as current designs puzzles allow proteins to be designed.

@@ Line 4: / Line 4: @@
 Try to complete each puzzle without help first. Most of the puzzles should take only a couple of minutes. If you get stuck, use "Reset Puzzle" from the Actions menu in the lower left and try again.
-'''New:''' the video [https://www.youtube.com/watch?v=bIc-FoHLtjY QUICK Foldit Tutorial Walkthrough] from S0ckrates shows you how to be the boss of the intro puzzles.
+'''Note:''' the video [https://www.youtube.com/watch?v=bIc-FoHLtjY QUICK Foldit Tutorial Walkthrough] from S0ckrates shows you how to be the boss of the intro puzzles.
 [[Intro Puzzles/Tips|Intro Puzzle Tips]] covers some common questions like how to [[Band|band]] and [[Freeze|freeze]]. It also gives some keyboard shortcuts for view options that may help you see what's going on.
@@ Line 18: / Line 18: @@
 [http://ja.foldit.wikia.com/wiki/Tutorial_Puzzles | Japanese].
 __NOEDITSECTION__
+The campaign puzzles are arranged in levels. Each level covers a different part of Foldit. You earn a Foldit achievement when you complete a level.
-Intro puzzles are organized into levels. Click on the icons below for more information about each intro puzzle. The [[Intro Puzzles/Master List|Intro Puzzle Master List]] has the same information in a simplified format.
+There are different paths through the levels. The paths may allow you to move on to a new level if you get stuck on a particular puzzle. You can always come back later to finish a problem puzzle.
+Click on the icons below for more information about each intro puzzle. The [[Intro Puzzles/Master List|Intro Puzzle Master List]] has the same information in a simplified format.
 ==Sidechains==
@@ Line 45: / Line 49: @@
 <gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
 Sheets_Together.png|Sheets Together|link=Intro_Puzzles/Sheets_Together
-Lonely_Sheets.png|Lonely Sheets|link=Intro_Puzzles/Lonely_Sheets
 Lock_and_Lower.png|Lock and Lower|link=Intro_Puzzles/Lock_and_Lower
+Lonely_Sheets.png|Lonely Sheets|link=Intro_Puzzles/Lonely_Sheets
 Sheets_and_Ladders.png|Sheets and Ladders|link=Intro_Puzzles/Sheets_and_Ladders
 Hide_the_Hydrophobic.png|Hide the Hydrophobic|link=Intro_Puzzles/Hide_the_Hydrophobic
-Hydrophobic_Disaster.png|Hydrophobic Disaster|link=Intro_Puzzles/Hydrophobic_Disaster
+Turn_It_Down.png|Turn It Down|link=Intro_Puzzles/Turn_It_Down
+Flippin'_Sheets.png|Flippin' Sheets|link=Intro_Puzzles/Flippin'_Sheets
+Control_Over_Clashing.png|Control Over Clashing|link=Intro_Puzzles/Control_Over_Clashing
 </gallery>
 ==Hydrophobics and Hydrophilics==
-This level discusses [[Hydrophobic|hydrophobics]] and [[Hydrophilic|hydrophilics]] in more detail. Orange sidechains are hydrophobic, and should be hidden on the inside of the protein. Blue sidechains are hydrophilic, and are OK on the outside of the protein.
+This level digs itno [[Hydrophobic|hydrophobics]] and [[Hydrophilic|hydrophilics]] in more detail. Orange sidechains are hydrophobic, and should be hidden on the inside of the protein. Blue sidechains are hydrophilic, and are OK on the outside of the protein.
 <gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
-Control_Over_Clashing.png|Control Over Clashing|link=Intro_Puzzles/Control_Over_Clashing
+Hydrophobic_Disaster.png|Hydrophobic Disaster|link=Intro_Puzzles/Hydrophobic_Disaster
-Turn_It_Down.png|Turn It Down|link=Intro_Puzzles/Turn_It_Down
-Flippin'_Sheets.png|Flippin' Sheets|link=Intro_Puzzles/Flippin'_Sheets
 The_Right_Rotation.png|The Right Rotation|link=Intro_Puzzles/The_Right_Rotation
 </gallery>
-==Tools and Types==
+==Protein Design==
+This level introduces Foldit [[Design puzzle|design puzzles]], which give players the chance to design new proteins. Some of these designs actually get turned into real proteins in the Foldit lab, see [[Design puzzle results|design puzzle results]] for more.
-The Tools and Types level introduces some of the different [[101_-_Puzzle_Levels_and_Types|puzzle types]] found in Foldit. The move tool is added.
-This level also introduces the [[Remix|remix]] tool, which searches for new shapes for your protein.
 <br clear="all"/>
 <gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
-Quest_to_the_Native.png|Quest to the Native|link=Intro_Puzzles/Quest_to_the_Native
+Intro_to_Design.png|Intro to Design|link=Intro_Puzzles/Intro_to_Design
-Movin'_Along.png|Movin' Along|link=Intro_Puzzles/Movin'_Along
+Swappin'_Sidechains.png|Swappin' Sidechains|link=Intro_Puzzles/Swappin'_Sidechains
-Electron_Density.png|Electron Density|link=Intro_Puzzles/Electron_Density
+Mass_Mutate.png|Mass Mutate|link=Intro_Puzzles/Mass_Mutate
-Remix.png|Remix|link=Intro_Puzzles/Remix
+Insertion_and_Deletion.png|Insertion and Deletion|link=Intro_Puzzles/Insertion_and_Deletion
+DNA_Pairing.png|DNA Pairing|link=Intro_Puzzles/DNA_Pairing
+DNA_and_Protein.png|DNA and Protein|link=Intro_Puzzles/DNA_and_Protein
 </gallery>
+==Conditional Quests==
-==Sequences==
-Sequences introduces the alignment tool. The alignment tool lets you apply the shapes of other proteins to the protein you're working on.
-You'll also get to use [[Cutpoints|cuts]], which chop a protein into pieces. Cuts are used in all kinds of ways in Foldit.
-<br clear="all"/>
-<gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
-Structure_and_Idealize.png|Structure and Idealize|link=Intro_Puzzles/Structure_and_Idealize
-Basic_Threading.png|Basic Threading|link=Intro_Puzzles/Basic_Threading
-Cut_and_Paste.png|Cut and Paste|link=Intro_Puzzles/Cut_and_Paste
-Alignin'_Sequences.png|Alignin' Sequences|link=Intro_Puzzles/Alignin'_Sequences
-</gallery>
-==Conditions==
 This level covers [[Conditions|conditions]], which enforce special rules on some puzzles. Conditions may change your score, adding or subtracting points. Conditions were previously called "filters".
 <br clear="all"/>
 <gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
 Make_Five_Bonds_(icon).png|Make Five Bonds|link=Intro_Puzzles/Make_Five_Bonds
 Disulfide_Bonds_(icon).png|Disulfide Bonds|link=Intro_Puzzles/Disulfide_Bonds
 Combo_Conditions_(icon).png|Combo Conditions|link=Intro_Puzzles/Combo_Conditions
 </gallery>
-==Blueprint==
+==Blueprints==
 This level introduces the blueprint tool, which is used in [[Design puzzle|design puzzles]] to insert shapes found in natural proteins. The blueprint tool may help players create proteins which fold up on their own like natural ones. Design puzzles are covered in more detail in the next section.
 <br clear="all"/>
@@ Line 97: / Line 91: @@
 Blueprint_and_Condition_(icon).png|Blueprint and Condition|link=Intro_Puzzles/Blueprint_and_Condition
 </gallery>
-==Protein Design==
+==Tools and Types==
+The Tools and Types level introduces some of the different [[101_-_Puzzle_Levels_and_Types|puzzle types]] found in Foldit. The move tool is added.
-This level introduces Foldit [[Design puzzle|design puzzles]], which give players the chance to design new proteins. Some of these designs actually get turned into real proteins in the Foldit lab, see [[Design puzzle results|design puzzle results]] for more.
+This level also introduces the [[Remix|remix]] tool, which searches for new shapes for your protein.
 <br clear="all"/>
 <gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
-Intro_to_Design.png|Intro to Design|link=Intro_Puzzles/Intro_to_Design
+Movin'_Along.png|Movin' Along|link=Intro_Puzzles/Movin'_Along
-Swappin'_Sidechains.png|Swappin' Sidechains|link=Intro_Puzzles/Swappin'_Sidechains
+Remix.png|Remix|link=Intro_Puzzles/Remix
-Mass_Mutate.png|Mass Mutate|link=Intro_Puzzles/Mass_Mutate
+Quest_to_the_Native.png|Quest to the Native|link=Intro_Puzzles/Quest_to_the_Native
-Insertion_and_Deletion.png|Insertion and Deletion|link=Intro_Puzzles/Insertion_and_Deletion
+Electron_Density.png|Electron Density|link=Intro_Puzzles/Electron_Density
+</gallery>
+==Sequences==
+Sequences introduces the alignment tool. The alignment tool lets you apply the shapes of other proteins to the protein you're working on.
+You'll also get to use [[Cutpoints|cuts]], which chop a protein into pieces. Cuts are used in all kinds of ways in Foldit.
+<br clear="all"/>
+<gallery widths="120" spacing="small" captionsize="small" captionalign="center" navigation="true" hideaddbutton="true">
+Structure_and_Idealize.png|Structure and Idealize|link=Intro_Puzzles/Structure_and_Idealize
+Basic_Threading.png|Basic Threading|link=Intro_Puzzles/Basic_Threading
+Cut_and_Paste.png|Cut and Paste|link=Intro_Puzzles/Cut_and_Paste
+Alignin'_Sequences.png|Alignin' Sequences|link=Intro_Puzzles/Alignin'_Sequences
 </gallery>
 ==More Molecules==
@@ Line 114: / Line 121: @@
 Ligand_Debut.png|Ligand Debut|link=Intro_Puzzles/Ligand_Debut
 Ligand_Constraints.png|Ligand Constraints|link=Intro_Puzzles/Ligand_Constraints
-DNA_Pairing.png|DNA Pairing|link=Intro_Puzzles/DNA_Pairing
-DNA_and_Protein.png|DNA and Protein|link=Intro_Puzzles/DNA_and_Protein
 </gallery>
 [[Category:Help]]