Foldit Wiki

Here are the Campaign puzzles, in order, as of December 2021.

The entry for each puzzle links to the puzzle's help page, and YouTube videos from Madde and Loci.

The videos don't have any voice narration, but they do include Foldit sound effects.

Madde's videos date back a few years. You may see some differences in the current intro puzzles, such as additional help popups. Some of Madde's videos were made using a German client, which ends up being a mix of German and English.

Loci's videos were created using the June 2018 release of Foldit, and are all in English. They include the newer intro puzzles, such as the ones introduced in November, 2017.

As of late 2021, there are some newer puzzles, which don't have puzzle pages or videos yet. All the puzzles need new videos due to recent changes in the Foldit user interface.

# help video M video L
1 One Small Clash Madde Loci
2 Swing It Around Madde Loci
3 Shake! Madde Loci
4 Backbones Collide Madde Loci
5 Close the Gap Madde Loci
6 Wiggle! Madde Loci
7 Sheets Together Madde Loci
8 Lonely Sheets Madde Loci
9 Lock and Lower Madde Loci
10 Sheets and Ladders Madde Loci
11 Hide the Hydrophobic Madde Loci
12 Hydrophobic Disaster Loci
13 Control Over Clashing Madde Loci
14 Turn It Down Madde Loci
15 Flippin' Sheets Madde Loci
16 The Right Rotation Madde Loci
17 Quest to the Native Madde Loci
18 Movin' Along Madde Loci
19 Electron Density Madde Loci
20 Remix Loci
21 Cut and Paste Madde Loci
22 Make Five Bonds Loci
23 Hello Blueprint Loci
24 More Building Blocks Loci
25 Intro to Design Madde Loci
26 Swappin' Sidechains Madde Loci
27 Mass Mutate Madde Loci
28 Insertion and Deletion Madde Loci
29 Ligand Debut Madde Loci
30 Inside the Pocket
31 Fun with Fragments!
32 Reaction Design
33 Ligand Constraints Madde Loci
34 De-Novo: Final Test