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The action bar, as seen in the new interface. The action bar contains icons for all tools available in the current puzzle. Some icons may be grayed out if a required selection or other conditions are not present.

The action bar is a feature of the Foldit new interface and its predecessor, the selection interface.

The action bar displays icons for all tools available for the current puzzle. In the new interface, these icons are always displayed. The selection interface hid icons for tools until requirements such as a selection or the presence of bands was met. In the new interface, icons are grayed out if the requirements for a specific tool aren't met.

The image shows a typical action bar. The exact layout of the bar depends on the screen size. On a smaller screen, the icons may be stacked into more rows. Not all puzzles will have the same set of icons.

The icons shown in the image can be identified by the keyboard shortcut. In the top row, the icons and their requirements are:

  • B - toggle Blueprint window (no selection required)
  • P - toggle Rama Map (no selection required)
  • 4 - remix (between 3 and 9 contiguous segments must be selected, with no cutpoints)
  • O - rebuild (disabled on recent design puzzles, a selection must be present)
  • 2 - Idealize peptide bonds (two or more contiguous segments selected)
  • 3 - toggle move tool
  • C - open cutpoint (exactly two adjacent segments must be selected)

In the second row, the icons and their requirements are:

  • F - freeze/unfreeze (freezes or unfreezes all if nothing is selected)
  • W - wiggle (wiggles all if nothing is selected)
  • E - wiggle sidechains (wiggles all sidechains if nothing is selected)
  • T - wiggle backbone (wiggles all backbone if nothing is selected)
  • Y - mutate (mutates all if nothing is selected)
  • S - shake (shakes all if nothing is selected)
  • A - pick sidechains (picks sidechains for all segments if nothing is selected)
  • 1 - toggle display of segment notes
  • R - remove bands (one or more bands must be present)
  • D - disable/enable bands (one or more bands must be present)
  • L - set secondary structure (one or more segments must be selected)
  • 5 - idealize secondary structure (one or more segments must be selected)
  • M - mutate to a specific amino acid (one or more segments must be selected)
  • X - delete segments (one or more segments must be selected)
  • I - insert segments (one or two segments must be selected)

Some design puzzles consist of a mainly locked protein and another unlocked protein or ligand. Locked segments can't be selected, and so they don't satisfy the requirements for action bar tools which require a selection.

Some tools require multiple segments to be selected. Left-clicking on a segment, the shift-left-clicking on a second segment is one way to select multiple segments. Double-left-clicking on a segment marked as sheet, helix, or loop selects all adjacent segments with the same secondary structure.

Control-left-clicking (command-left-click on Mac) can be used to fine-tune a selection containing multiple segments. Control-left-click selects or deselects a single segment.

Some tools require selected segments to be next to each other. That may be described as a "continuous", "contiguous", or "adjacent" selection, depending on the context. The idea is that the selection must contain a single uninterrupted sequence of segment numbers, for example segments 49 to 57.

Some puzzles contain multiple protein chains. A continuous selection can't start on one chain and continue on another. In most puzzles with multiple chains, one chain's backbone is locked, so none of its segments can be selected. But in Revisiting puzzle 58: Insulin Mutant, the two insulin chains are unlocked. The first chain ends on segment 21. So a selection starting with segment 20 and continuing to segment 24 will contain five segments, but it won't qualify as a continuous selection for the remix tool, since it crosses the boundary between chains. The rebuild tool, however, is happy to operate on a selection that crosses between chains.

A cutpoint may also break up a continuous selection. The remix tool won't accept a selection that contains a cutpoint. On the other hand, the rebuild tool will cheerfully rebuild a selection with a cutpoint.

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